2023
Young Hee Kim Byeol-A Yoon Young Rae Jo Soo Hyun Nam Nam Hee Kim Kyoung Hee Kim Jong Kuk Kim Byung-Ok Choi Hwan Tae Park. Neural cell adhesion molecule 1 is a cellular target engaged plasma biomarker in demyelinating Charcot-Marie-Tooth disease. Eur J Neurol. 2023 Jun;30(6):1745-1754. PMID: 36856547
Sang-Heum Han;Young Hee Kim;Su-Jeong Park;Jun-Gi Cho;Yoon Kyung Shin; Young Bin Hong; Jeanho Yun; Jin-Yeong Han; Hwan Tae Park;Joo-In Park.COUP-TFII plays a role in cAMP-induced Schwann cell differentiation and in vitro myelination by up-regulating Krox20. J Neurochem. 2023 Jun;165(5):660-681. PMID: 36648143
Shin, Yoon Kyung; Jo, Young Rae; Lee, Seoung Hoon; Park, Hwan Tae; Shin, Jung Eun; Regulation of the V-ATPase subunit ATP6V0D2 and its role in demyelination after peripheral nerve injury. Biochem Biophys Res Commun. 2023 Feb 26;646:1-7. PMID: 36689911
Jo, Young Rae; Oh, Yuna; Kim, Young Hee; Shin, Yoon Kyung; Kim, Hye Ran; Go, Hana; Shin, Jaekyoon; Park, Hye Ji; Koh, Hyongjong; Kim, Jong Kuk; Shin, Jung Eun; Lee, Kyung Eun; Park, Hwan Tae; Adaptive autophagy reprogramming in Schwann cells during peripheral demyelination. Cell Mol Life Sci. 2023 Jan 9;80(1):34. PMID: 36622429
2022
Cho, Jun Gi; Park, Su-Jeong; Han, Sang-Heum; Park, Joo-In; PGC-1 alpha Regulates Cell Proliferation, Migration, and Invasion by Modulating Leucyl-tRNA Synthetase 1 Expression in Human Colorectal Cancer Cells. Cancers (Basel). 2022 Dec 27;15(1):159. PMID: 36612155
Kim, Hye Young; Park, Chul Hee; Park, Joon Beom; Ko, Kangeun; Lee, Mi Hwa; Chung, Jin; Yoo, Young Hyun; Hepatic STAMP2 alleviates polychlorinated biphenyl-induced steatosis and hepatic iron overload in NAFLD models. Environ Toxicol . 2022 Sep;37(9):2223-2234. PMID: 35616167
Nam, Da Eun; Park, Jin Hee; Park, Cho Eun; Jung, Na Young; Nam, Soo Hyun; Kwon, Hye Mi; Kim, Hyun Su; Kim, Sang Beom; Son, Won Seok; Choi, Byung-Ok; Chung, Ki Wha; Variants of aminoacyl-tRNA synthetase genes in Charcot-Marie-Tooth disease: A Korean cohort study. J Peripher Nerv Syst. 2022 Mar;27(1):38-49. PMID: 34813128
2021
Kim HS, Lee JH, Yoon YC, Cha MJ, Nam SH, Kwon HM, Kim S, Won H, Choi BO. Intraepineurial fat quantification and cross-sectional area analysis of the sciatic nerve in Charcot-Marie-Tooth disease type 1A patients using MRI. Sci Rep. 2021 Nov 2;11(1):21535. doi: 10.1038/s41598-021-00819-0. PMID: 34728674. PMCID: PMC8563983.
Byeon JW, Jo YR, Shin YK, Park HT, Park HS. caffolding protein Gab2 is involved in postnatal development and lipopolysaccharide-induced activation of microglia in the mouse brain. Biochemical and Biophysical Research Communications. 2021 Aug 27;567:112-117. doi: 10.1016/j.bbrc.2021.06.028. Epub 2021 Jun 17. PMID: 34146905.
Kim J, Nam SH, Kim JH, Han J. Current Stem Cell Research Status on Hepatic and Pulmonary Sclerosis in COVID-19. J Biomed Res Environ Sci. 2021 Apr 22; 2(4): 292-295. doi: 10.37871/jbres1228, Article ID: JBRES1228
Kwon HM, Kim HS, Kim SB, Park JH, Nam DE, Lee AJ, Nam SH, Hwang S, Chung KW, Choi BO. Clinical and Neuroimaging Features in Charcot-Marie-Tooth Patients with GNB4 Mutations. Life (Basel). 2021 May 28;11(6):494. doi: 10.3390/life11060494. PMID: 34071515. PMCID: PMC8227704.
Kim HJ, Nam SH, Kwon HM, Lim SO, Park JH, Kim HS, Kim SB, Lee KS, Lee JE, Choi BO, Chung KW. Genetic and clinical spectrums in Korean Charcot-Marie-Tooth disease patients with myelin protein zero mutations. Mol Genet Genomic Med. 2021 Jun;9(6):e1678. doi: 10.1002/mgg3.1678. Epub 2021 Apr 6. PMID: 33825325. PMCID: PMC8222852
Yoon BA, Ha DH, Park HT, Kusunoki S, Kuwahara M, Lee JH, Bae JS, Kim JK. Finger drop sign as a new variant of acute motor axonal neuropathy. Muscle Nerve. 2021 Mar;63(3):336-343. doi: 10.1002/mus.27126. Epub 2020 Dec 22. PMID: 33217007
Hwang SH, Chang EH, Kwak G, Jeon H, Choi BO, Hong YB. Gait parameters as tools for analyzing phenotypic alterations of a mouse model of Charcot-Marie-Tooth disease. Anim Cells Syst (Seoul). 2021 Feb 11;25(1):11-18.
doi: 10.1080/19768354.2021.1880967. PMID: 33717412. PMCID: PMC7935128.
Kim HS, Kim HJ, Nam SH, Kim SB, Choi YJ, Lee KS, Chung KW, Yoon YC, Choi BO. Clinical and Neuroimaging Features in Charcot-Marie-Tooth Patients with GDAP1 Mutations.J Clin Neurol. 2021 Jan;17(1):52-62. doi: 10.3988/jcn.2021.17.1.52. PMID: 33480199. PMCID: PMC7840330.
Jo YR, Kim HR, Jang SY, Go H, Song MY, Park DK, Oh Y, Jo J, Shin YK, Lee SJ, Cheon SM, Lee HK, Lee KE, Kim YH, Park HT. Potential neuron-autonomous Purkinje cell degeneration by 2',3'-cyclic nucleotide 3'-phosphodiesterase promoter/ Cre-mediated autophagy impairments. The FASEB Journal. 2021 Jan;35(1):e21225. doi: 10.1096/fj.202001366RR. PMID: 33337568.
2020
Kim HY, Kwon WY, Park JB, Lee MH, Oh YJ, Suh S, Baek YH, Jeong JS, Yoo YH.
Hepatic STAMP2 mediates recombinant FGF21-induced improvement of hepatic iron overload in nonalcoholic fatty liver disease. FASEB J. 2020 Jul 28. doi: 10.1096/fj.202000790R. Epub ahead of print. PMID: 32721044. 10.1007/s13258-020-00933-9. Epub 2020 Apr 20. PMID: 32314272.
Park HT, Kim YH, Lee KE, Kim JK. Behind the pathology of macrophage- associated demyelination in inflammatory neuropathies: demyelinating Schwann cells. Cell Mol Life Sci. 2020 Jul;77(13):2497-2506. doi:
10.1007/s00018-019-03431-8. Epub 2019 Dec 28. PMID: 31884566; PMCID: PMC7320037.
Lee AJ, Nam DE, Choi YJ, Nam SH, Choi BO, Chung KW. Alanyl-tRNA synthetase 1 (AARS1) gene mutation in a family with intermediate Charcot-Marie-Tooth neuropathy. Genes Genomics. 2020 Jun;42(6):663-672. doi: 10.1007/s13258-020-00933-9. Epub 2020 Apr 20. PMID: 32314272.
Choi JE, Seol HY, Seok JM, Hong SH, Choi BO, Moon IJ. Psychoacoustics and neurophysiological auditory processing in patients with Charcot-Marie-Tooth disease types 1A and 2A. Eur J Neurol. 2020 Jun 1. doi: 10.1111/ene.14370. Epub ahead of print. PMID: 32478888.
Sohn EJ, Park HT, Shin YK. Exosomes derived from differentiated Schwann cells inhibit Schwann cell migration via microRNAs. Neuroreport. 2020 May 7;31(7):515-522. doi: 10.1097/WNR.0000000000001435. PMID: 32282580.
Yun SH, Park JI. Recent progress on the role and molecular mechanism of chicken ovalbumin upstream promoter-transcription factor II in cancer. J Int Med Res. 2020 Apr;48(4):300060520919236. doi: 10.1177/0300060520919236. PMID: 32338091; PMCID: PMC7218465.
Kim YY, Um JH, Yoon JH, Lee DY, Lee YJ, Kim DH, Park JI, Yun J. p53 regulates mitochondrial dynamics by inhibiting Drp1 translocation into mitochondria during cellular senescence. FASEB J. 2020 Feb;34(2):2451-2464. doi: 10.1096/fj.201901747RR. Epub 2019 Dec 13. PMID: 31908078.
Yun SH, Park JI. PGC-1α Regulates Cell Proliferation and Invasion via AKT/GSK-3β/β-catenin Pathway in Human Colorectal Cancer SW620 and SW480 Cells. Anticancer Res. 2020 Feb;40(2):653-664. doi: 10.21873/anticanres.13995. PMID: 32014906.
Sohn EJ, Park HT. Differential expression of circular RNAs in the proximal and distal segments of the sciatic nerve after injury. Neuroreport. 2020 Jan 8;31(1):76-84. doi: 10.1097/WNR.0000000000001371. PMID: 31764243.
Kang KH, Han JE, Hong YB, Nam SH, Choi BO, Koh H. Human HSPB1 mutation recapitulates features of distal hereditary motor neuropathy (dHMN) in Drosophila. Biochem Biophys Res Commun. 2020 Jan 1;521(1):220-226. doi: 10.1016/j.bbrc.2019.10.110. Epub 2019 Oct 17. PMID: 31630804.
2019
Kang KH, Han JE, Hong YB, Nam SH, Choi BO, Koh H. Human HSPB1 mutation recapitulates features of distal hereditary motor neuropathy (dHMN) in Drosophila. Biochem Biophys Res Commun. 2020 Jan 1;521(1):220-226. doi: 10.1016/j.bbrc.2019.10.110. Epub 2019 Oct 17. PMID: 31630804.
Kim YY, Um JH, Yoon JH, Kim H, Lee DY, Lee YJ, Jee HJ, Kim YM, Jang JS, Jang YG, Chung J, Park HT, Finkel T, Koh H, Yun J. Assessment of mitophagy in mt-Keima Drosophila revealed an essential role of the PINK1-Parkin pathway in mitophagy induction in vivo. FASEB J. 2019 Sep;33(9):9742-9751. doi:10.1096/fj.201900073R. Epub 2019 May 23. PMID: 31120803.
Sohn EJ, Jo YR, Park HT. Downregulation MIWI-piRNA regulates the migration of Schwann cells in peripheral nerve injury. Biochem Biophys Res Commun. 2019 Nov 12;519(3):605-612. doi: 10.1016/j.bbrc.2019.09.008. Epub 2019 Sep 17. PMID: 31540693.
Chang EH, Mo WM, Doo HM, Lee JS, Park HT, Choi BO, Hong YB. Aminosalicylic acid reduces ER stress and Schwann cell death induced by MPZ mutations. Int JMol Med. 2019 Jul;44(1):125-134. doi: 10.3892/ijmm.2019.4178. Epub 2019 May 2. PMID: 31059078; PMCID: PMC6559330.
Kim YH, Kim YH, Shin YK, Jo YR, Park DK, Song MY, Yoon BA, Nam SH, Kim JH, Choi BO, Shin HY, Kim SW, Kim SH, Hong YB, Kim JK, Park HT. p75 and neural cell adhesion molecule 1 can identify pathologic Schwann cells in peripheral neuropathies. Ann Clin Transl Neurol. 2019 Jul;6(7):1292-1301. doi: 10.1002/acn3.50828. Epub 2019 Jul 2. PMID: 31353867; PMCID: PMC6649441.
Park HT, Kim JK, Tricaud N. The conceptual introduction of the "demyelinating Schwann cell" in peripheral demyelinating neuropathies. Glia. 2019 Apr;67(4):571-581. doi: 10.1002/glia.23509. Epub 2018 Oct 30. PMID: 30378179.
Sohn EJ, Nam YK, Park HT. MicroRNAs 93-5p, 106b-5p, 17-5p, and 140-5p target the expression of early growth response protein 2 in Schwann cells. Neuroreport. 2019 Feb 6;30(3):241-246. doi: 10.1097/WNR.0000000000001193. PMID: 30614908.
Kim SY, Jin CY, Kim CH, Yoo YH, Choi SH, Kim GY, Yoon HM, Park HT, Choi YH. Isorhamnetin alleviates lipopolysaccharide-induced inflammatory responses in BV2 microglia by inactivating NF-κB, blocking the TLR4 pathway and reducing ROS generation. Int J Mol Med. 2019 Feb;43(2):682-692. doi: 10.3892/ijmm.2018.3993. Epub 2018 Nov 20. PMID: 30483725; PMCID: PMC6317673.
Kim YA, Park JB, Woo MS, Lee SY, Kim HY, Yoo YH. Persistent Organic Pollutant-Mediated Insulin Resistance. Int J Environ Res Public Health. 2019 Feb 3;16(3):448. doi: 10.3390/ijerph16030448. PMID: 30717446; PMCID: PMC6388367.
Park C, Choi EO, Kim GY, Hwang HJ, Kim BW, Yoo YH, Park HT, Choi YH. Protective Effect of Baicalein on Oxidative Stress-induced DNA Damage and Apoptosis in RT4-D6P2T Schwann Cells. Int J Med Sci. 2019 Jan 1;16(1):8-16. doi: 10.7150/ijms.29692. PMID: 30662323; PMCID: PMC6332490.
Jeong JY, Cha HJ, Choi EO, Kim CH, Kim GY, Yoo YH, Hwang HJ, Park HT, Yoon HM, Choi YH. Activation of the Nrf2/HO-1 signaling pathway contributes to the protective effects of baicalein against oxidative stress-induced DNA damage and apoptosis in HEI193 Schwann cells. Int J Med Sci. 2019 Jan 1;16(1):145-155. doi: 10.7150/ijms.27005. PMID: 30662338; PMCID: PMC6332480.
2018
Sohn EJ, Bak KM, Nam YK, Park HT. Upregulation of microRNA 344a-3p is involved in curcumin induced apoptosis in RT4 schwannoma cells. Cancer Cell Int. 2018 Dec 4;18:199. doi: 10.1186/s12935-018-0693-x. PMID: 30534000; PMCID: PMC6278133.
Lee SW, Park JB, Kim HJ, Kim HY, Lee SY, Chung WT, Shin YK, Park HT, Rho JH, Yoo YH. Palmitate induces lipoapoptosis in Schwann cells through ROS generation-mediated STAMP2 downregulation. Biochem Biophys Res Commun. 2018 Sep 10;503(3):1260-1266. doi: 10.1016/j.bbrc.2018.07.034. Epub 2018 Jul 11. PMID: 30005874.
Yun SH, Sim EH, Han SH, Han JY, Kim SH, Silchenko AS, Stonik VA, Park JI. Holotoxin A₁ Induces Apoptosis by Activating Acid Sphingomyelinase and Neutral Sphingomyelinase in K562 and Human Primary Leukemia Cells. Mar Drugs. 2018 Apr 10;16(4):123. doi: 10.3390/md16040123. PMID: 29642569; PMCID: PMC5923410.
Sohn EJ, Park HT. MicroRNA Mediated Regulation of Schwann Cell Migration and Proliferation in Peripheral Nerve Injury. Biomed Res Int. 2018 Apr 30;2018:8198365. doi: 10.1155/2018/8198365. PMID: 29854793; PMCID: PMC5952561.
Yun SH, Roh MS, Jeong JS, Park JI. Peroxisome proliferator-activated receptor γ coactivator-1α is a predictor of lymph node metastasis and poor prognosis in human colorectal cancer. Ann Diagn Pathol. 2018 Apr;33:11-16. doi: 10.1016/j.anndiagpath.2017.11.007. Epub 2017 Nov 10. PMID: 29566941.
Nam DE, Nam SH, Lee AJ, Hong YB, Choi BO, Chung KW. Small heat shock protein B3 (HSPB3) mutation in an axonal Charcot-Marie-Tooth disease family. J Peripher Nerv Syst. 2018 Mar;23(1):60-66. doi: 10.1111/jns.12249. Epub 2018 Feb 6. PMID: 29341343.
2017
Yun SH, Shin SW, Park JI. Expression of fatty acid synthase is regulated by PGC‑1α and contributes to increased cell proliferation. Oncol Rep. 2017 Dec;38(6):3497-3506. doi: 10.3892/or.2017.6044. Epub 2017 Oct 18. PMID: 29130104.
Sohn EJ, Park HT. Natural agents mediated autophagic signal networks in cancer. Cancer Cell Int. 2017 Nov 28;17:110. doi: 10.1186/s12935-017-0486-7. PMID: 29209152; PMCID: PMC5704453.
Yun SH, Park MG, Kim YM, Roh MS, Park JI. Expression of chicken ovalbumin upstream promoter-transcription factor II and liver X receptor as prognostic indicators for human colorectal cancer. Oncol Lett. 2017 Oct;14(4):4011-4020. doi: 10.3892/ol.2017.6659. Epub 2017 Jul 24. PMID: 28943908; PMCID: PMC5594251.
Yang J, Kim MJ, Yoon W, Kim EY, Kim H, Lee Y, Min B, Kang KS, Son JH, Park HT, Chung J, Koh H. Isocitrate protects DJ-1 null dopaminergic cells from oxidative stress through NADP+-dependent isocitrate dehydrogenase (IDH). PLoS Genet. 2017 Aug 21;13(8):e1006975. doi: 10.1371/journal.pgen.1006975. PMID: 28827794; PMCID: PMC5578699.
Jang SY, Yoon BA, Shin YK, Yun SH, Jo YR, Choi YY, Ahn M, Shin T, Park JI, Kim JK, Park HT. Schwann cell dedifferentiation-associated demyelination leads to exocytotic myelin clearance in inflammatory segmental demyelination. Glia. 2017 Nov;65(11):1848-1862. doi: 10.1002/glia.23200. Epub 2017 Aug 10. PMID: 28795433.
Park SY, Jang SY, Shin YK, Yoon BA, Lee HJ, Park HT. Grb2-associated binder-1 is required for extrafusal and intrafusal muscle fiber development. Neuroreport. 2017 Jul 5;28(10):604-609. doi: 10.1097/WNR.0000000000000807. PMID: 28542067.
Ghidinelli M, Poitelon Y, Shin YK, Ameroso D, Williamson C, Ferri C, Pellegatta M, Espino K, Mogha A, Monk K, Podini P, Taveggia C, Nave KA, Wrabetz L, Park HT, Feltri ML. Laminin 211 inhibits protein kinase A in Schwann cells to modulate neuregulin 1 type III-driven myelination. PLoS Biol. 2017 Jun 21;15(6):e2001408. doi: 10.1371/journal.pbio.2001408. PMID: 28636612; PMCID: PMC5479503.
Shin YK, Jang SY, Yun SH, Choi YY, Yoon BA, Jo YR, Park SY, Pak MG, Park JI, Park HT. Cooperative interaction of hepatocyte growth factor and neuregulin regulates Schwann cell migration and proliferation through Grb2-associated binder-2 in peripheral nerve repair. Glia. 2017 Nov;65(11):1794-1808. doi: 10.1002/glia.23195. Epub 2017 Jul 19. PMID: 28722233.
Park SY, Jang SY, Shin YK, Jung DK, Yoon BA, Kim JK, Jo YR, Lee HJ, Park HT.
The Scaffolding Protein, Grb2-associated Binder-1, in Skeletal Muscles and Terminal Schwann Cells Regulates Postnatal Neuromuscular Synapse Maturation. Exp Neurobiol. 2017 Jun;26(3):141-150. doi: 10.5607/en.2017.26.3.141. Epub 2017 Jun 16. PMID: 28680299; PMCID: PMC5491582.
Tricaud N, Park HT. Wallerian demyelination: chronicle of a cellular cataclysm. Cell Mol Life Sci. 2017 Nov;74(22):4049-4057. doi: 10.1007/s00018-017-2565-2. Epub 2017 Jun 9. PMID: 28600652; PMCID: PMC5641270.
Kim HY, Kwon WY, Kim YA, Oh YJ, Yoo SH, Lee MH, Bae JY, Kim JM, Yoo YH.
Polychlorinated biphenyls exposure-induced insulin resistance is mediated by lipid droplet enlargement through Fsp27. Arch Toxicol. 2017 Jun;91(6):2353-2363. doi: 10.1007/s00204-016-1889-2. Epub 2016 Nov 11. PMID: 27837308.
2016
Yun SH, Shin SW, Stonik VA, Park JI. Ceramide as a Target of Marine Triterpene Glycosides for Treatment of Human Myeloid Leukemia. Mar Drugs. 2016 Nov 3;14(11):205. doi: 10.3390/md14110205. PMID: 27827870; PMCID: PMC5128748.
Lee SW, Rho JH, Lee SY, Yoo SH, Kim HY, Chung WT, Yoo YH. Alpha B-Crystallin Protects Rat Articular Chondrocytes against Casein Kinase II Inhibition-Induced Apoptosis. PLoS One. 2016 Nov 16;11(11):e0166450. doi: 10.1371/journal.pone.0166450. PMID: 27851782; PMCID: PMC5112790.
Choi SH, Kim YH, Quinti L, Tanzi RE, Kim DY. 3D culture models of Alzheimer's disease: a road map to a "cure-in-a-dish". Mol Neurodegener. 2016 Dec 9;11(1):75. doi: 10.1186/s13024-016-0139-7. PMID: 27938410; PMCID: PMC5148918.